Treatment

Group

Concentration of liver enzymes (u/l)

Bilirubin concentration (mg/dl)

AST

ALT

Direct

Indirect

Total

Normal Control

16.49 ± 1.98^c

136.96 ± 9.92^c

0.12 ± 0.07^a

2.47 ± 0.39^d

2.58 ± 0.34^c

CCl₄ only

26.06 ± 1.14^b

158.53 ± 4.70^b

0.24 ± 0.02^b

3.11 ± 0.56^c

3.34 ± 0.54^b

CCl₄ + silymarin

17.71 ± 3.65^c

142.53 ± 4.87^c

0.20 ± 0.02^d

2.24 ± 0.54^d

2.44 ± 0.56^c

CCl₄ + A.p. 100 mg/kg

18.00 ± 2.71^c

151.28 ± 8.84^c

0.23 ± 0.01^c

3.35 ± 0.25^bc

3.59 ± 0.24^b

CCl₄ + A.p. 200 mg/kg

17.36 ± 1.97^c

147.46 ± 6.48^c

0.24 ± 0.01^bc

2.81 ± 0.97^cd

3.04 ± 0.96^bc

CCl₄ + A.p. 500 mg/kg

16.41 ± 1.85^ac

128.49 ± 3.05^ac

0.20 ± 0.02^d

0.98 ± 0.31^a

1.18 ± 0.47^a