Therapeutic target

Compound

Cox-1/cox-2 inhibitors

Piroxicam

Aspirin

Sulindec

Celecoxib (cox-2 only)

Induction of apoptosis

Piroxicam

Sulindec

aspirin

Modulation of lipoxygenase

Piroxicam

Aspirin

Sulindec

Supprerssion of prostaglandin synthesis

Piroxicam

Aspirin

Sulindec

Celecoxib

Induction of cell cycle arrest

Sulindec

Celecoxib

Inhibition of angiogenesis

Aspirin

celecoxib