Therapeutic target | Compound |
Cox-1/cox-2 inhibitors | Piroxicam Aspirin Sulindec Celecoxib (cox-2 only) |
Induction of apoptosis | Piroxicam Sulindec aspirin |
Modulation of lipoxygenase | Piroxicam Aspirin Sulindec |
Supprerssion of prostaglandin synthesis | Piroxicam Aspirin Sulindec Celecoxib |
Induction of cell cycle arrest | Sulindec Celecoxib |
Inhibition of angiogenesis | Aspirin celecoxib |