Q 1

Did the study describe the method of embryo collection and genotyping?

1-Yes

2-No

3-NA

Q 2

Did the study describe eligibility criteria and methods used to select participants?

1-Yes

2-No

3-NA

Q 3

Were the statistical analysis reported?

1-Yes

2-No

3-NA

Q 4

Did the study describe the trial design?

1-Yes

2-No

3-NA

Q 5

Did the study explain sample size calculations

1-Yes

2-No

3-NA

Q 7

Did the study describe blinding?

1-Yes

2-No

3-NA

Q 8

What were the key limitations according to the authors?

Q9

Did the authors discuss the external validity?

1-Yes

2-No

3-NA

Q 10

Did the study describe eligibility criteria and methods used to select participants?

1-Yes

2-No

3-NA

Q 12

Was the association of genes with TMJ Disorders clearly described?

1-Yes

2-No

3-NA

Q 13

Was the study outcome defined?

1-Yes

2-No

3-NA

Q 14

Did the study describe any measures to minimize potential sources of bias?

1-Yes

2-No

3-NA

Q15

Did the study explain how was sample size arrived at?

1-Yes

2-No

3-NA

Q 18

What were the key limitations according to the authors?