Grades | Toxicities |
Grade 1 | A mild or minimal adverse event, usually asymptomatic, that does not interfere with any function and does not require treatment or intervention |
Grade 2 | Moderate adverse event, usually symptomatic, requiring interventions such as local treatments, they may or may not interfere with function but not interfere with activities of daily living |
Grade 3 | Severe adverse event requiring serious interventions or even hospitalization |
Grade 4 | Life-threatening or disabling adverse event; disability |
Grade 5 | Death related to the adverse event |