All grade

Grade ≥ 3

Hypertension

22 (84.6)

19 (73.1)

Fatigue

19 (73.1)

1 (3.8)

Hand-foot syndrome

16 (61.5)

3 (11.5)

Hypothyroidism

16 (61.5)

0

Dysphonia

15 (57.7)

0

Diarrhea

12 (46.2)

0

Decreased appetite

8 (30.8)

2 (7.7)

Stomatitis

8 (30.8)

0

Rash

6 (23.1)

1 (3.8)

Dysgeusia

5 (19.2)

0

Nausea

4 (15.4)

2 (7.7)

Vomiting

4 (15.4)

0

Constipation

4 (15.4)

0

Laboratory abnormalities

Proteinurea

20 (76.9)

5 (19.2)

Blood uric acid increased

11 (42.3)

0

Blood creatinine increased

8 (30.8)

0

ALT increased

8 (30.8)

0

Thrombocytopenia

8 (30.8)

0

Anemia

5 (19.2)

1 (3.8)

AST increased

5 (19.2)

0