Biochemical parameter (unit) |
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| Post hoc comparisons across study periods*** | |||
T0a | T1a | T2a | P value** | χ2 | F | Effect size | T0 vs T1 | T0 vs T2 | T1 vs T2 | |
Total cholesterol (mg/dl) | 206.04 ± 40.33 | 189.43 ± 44.89 | 199.56 ± 37.91 | 0.004 |
| 6.13 | 0.358 | 0.01 | 0.04 | 0.72 |
LDL-cholesterol (mg/dl) | 133.09 ± 36.52 | 119.18 ± 36.66 | 128.95 ± 34.38 | 0.004 |
| 7.39 | 0.402 | 0.003 | 0.004 | 0.9 |
HDL-cholesterol (mg/dl) | 56.22 ± 15.34 | 53.21 ± 13.89 | 52.47 ± 14.01 | 0.11 |
| 2.33 | - | - | - | - |
LDL/HDL ratio | 2.58 ± 1.07 | 2.35 ± 0.87 | 2.66 ± 1.04 | 0.003 |
| 6.87 | 0.384 | 0.02 | 0.004 | 0.9 |
Triacylglyerols (mg/dl) | 104.48 ± 38.44 | 106.00 ± 37.90 | 113.96 ± 46.69 | 0.43 |
| 0.86 | - | - | - | - |
Uric acid (mg/dl) | 4.66 ± 0.90 | 4.31 ± 0.73 | 4.66 ± 0.89 | 0.007 |
| 5.51 | 0.334 | 0.025 | 0.99 | 0.013 |
Serum creatinine (mg/dl) | 0.94 ± 0.18 | 0.93 ± 0.15 | 0.82 ± 0.18 | <0.001 | 37.72 |
| 0.711 | 0.29 | <0.001 | <0.001 |
Azotemia (mg/dl) | 33.01 ± 9.96 | 32.13 ± 9.72 | 35.5 ± 12.19 | 0.10 |
| 2.84 | - | - | - | - |
Serum iron (mg/dl) | 100.68 ± 24.33 | 91.95 ± 33.66 | 83.78 ± 19.74 | 0.12 |
| 2.23 | - | - | - | - |
Glycemia (mg/dl) | 86.25 ± 5.90 | 85.82 ± 0.69 | 86.00 ± 6.69 | 0.82 |
| 0.19 | - | - | - | - |
ALTa (U/l) | 30.09 ± 12.12 | 35.22 ± 9.52 | 31.52 ± 9.73 | 0.03 |
| 4.43 | 0.287 | 0.011 | 0.065 | 0.99 |
ASTb (U/l) | 29.48 ± 7.08 | 30.30 ± 6.11 | 29.74 ± 5.55 | 0.54 | 1.22 |
| - | - | - | - |
GGTc (U/l) | 38.04 ± 8.77 | 35.27 ± 6.30 | 36.26 ± 6.54 | 0.03 | 11.41 |
| 0.284 | 0.001 | 0.31 | 0.16 |
Total bilirubin (mg/dl) | 0.83 ± 0.28 | 0.76 ± 0.24 | 0.88 ± 0.30 | 0.45 | 1.60 |
| - | - | - | - |
Hbd (mg/dl) | 14.54 ± 1.29 | 14.43 ± 1.30 | 14.46 ± 1.34 | 0.75 |
| 0.29 | - | - | - | - |
WBCse (µl) | 5894.26 ± 1204.55 | 5961.30 ± 1660.25 | 5862.60 ± 1006.71 | 0.96 | 0.09 |
| - | - | - | - |
RBCsf (µl) | 4,786,698.70 ± 456,834.83 | 4,771,347.83 ± 422,856.39 | 4,749,173.91 ± 463,205.50 | 0.37 |
| 0.83 | - | - | - | - |
PLTsg (µl) | 214,913.04 ± 40,648.06 | 221,121.74 ± 47,352.44 | 226,000 ± 42,664.50 | 0.24 |
| 1.46 | - | - | - | - |
Total plasma protein (mg/dl) | 6.99 ± 0.30 | 6.91 ± 0.34 | 6.99 ± 0.37 | 0.50 |
| 0.70 | - | - | - | - |