Variable

Total, n

Node negative n (%)

Node positive n (%)

p

Age at diagnosis

≤64 years

>64 years

73

67

43 (58.9)

45 (67.2)

30 (41.1)

22 (32.8)

0.40

Sex

Male

Female

112

28

73 (34.8)

15 (46.4)

39 (65.2)

13 (53.6)

0.36

Tumor site

Oral cavity

Pharynx

Larynx

57

27

56

40 (70.2)

3 (11.1)

45 (80.4)

17 (29.8)

24 (88.9)

11 (19.6)

<<0.0001

Differentiation

Well

Moderate and poor

89

51

64 (71.9)

24 (47.1)

25 (28.1)

27 (52.9)

0.014

T stage

T1, 2

T3, 4

62

78

46 (74.2)

42 (53.8)

16 (25.8)

36 (46.2)

0.021

VEGF-A

High > 2.74

Low ≤ 2.74

55

85

25 (45.5)

63 (74.1)

30 (54.5)

22 (25.9)

0.001

Ki-67

High > 58.61%

Low ≤ 58.61%

55

85

31 (56.4)

58 (68.2)

24 (43.6)

27 (31.8)

0.21

Combined expression

Both high

Either high

Neither high

27

59

54

11 (40.7)

36 (61)

41 (75.9)

16 (59.3)

23 (39)

13 (24.1)

0.008