| Parameter | Unit | Sibutramine |
|
|
|
| Source temperature | ˚C | 600.0 |
|
|
|
| Nebulizer gas | psi | 65 |
|
|
|
| Turbolon gas | psi | 65 |
|
|
|
| Curtain gas | psi | 35 |
|
|
|
| Collision gas | psi | 12 |
|
|
|
| Ion spray voltage | V | 2500 |
|
|
|
| Dwell time per transition | ms | 150 |
|
|
|
|
|
| Sibutramine | N-monodesmethylsibutramine | N-N-didesmethylsibutramine | Bisoprolol (IS) |
| Entrance potential | V | 7 | 15 | 10 | 15 |
| MRM transition | amu | 280.20 → 125.20 | 268.10 → 126.90 268.10 → 141.00 | 254.10 → 126.90 254.10 → 141.00 | 326.15 → 107.10 |
| Collision energy | V | 40 | 20 | 50 | 20 |
| Declustering potential | V | 125 | 50 | 25 | 90 |
| Collision cell exist potential | V | 40 | 15 | 10 | 15 |