CFRD N = 23

Matched controls N = 23

p-value

Current age

21.2 years (16.7 - 23.6)

20.7 years (16.0 - 23.5)

1.00

Gender F/M

14/9

14/9

1.00

Age at CF diagnosis

0.1 years (0 - 0.5)

0.1 years (0 - 0.1)

0.167

Age at CFRD diagnosis

14.0 years (13.4 - 17.0)

/

/

FEV1 % predicted at time zero

71.6 (59.2 - 89.2)

82.3 (57.8 - 92.5)

0.095

BMI Z-score at diagnosis

−0.89 (−2.23 - 0.42)

−0.71 (−1.29 - 0.16)

0.628

HbA1c at diagnosis

6.30 % (6.2% - 6.7%)

5.75% (5.5% - 6.1%)

<0.001

OGTT at time zero: fasting glycaemia

96 mg/dl (85 - 106)

/

/

OGTT at time zero: glycaemia at 120’

214 mg/dl (192 - 233)

/

/

F508 Homozygote

17/23

15/23

0.522

F508 Heterozygote/class I-III

5/23

8/23

0.326

No F508 deletion

1/23

0/23

0.321