| CFRD N = 23 | Matched controls N = 23 | p-value |
Current age | 21.2 years (16.7 - 23.6) | 20.7 years (16.0 - 23.5) | 1.00 |
Gender F/M | 14/9 | 14/9 | 1.00 |
Age at CF diagnosis | 0.1 years (0 - 0.5) | 0.1 years (0 - 0.1) | 0.167 |
Age at CFRD diagnosis | 14.0 years (13.4 - 17.0) | / | / |
FEV1 % predicted at time zero | 71.6 (59.2 - 89.2) | 82.3 (57.8 - 92.5) | 0.095 |
BMI Z-score at diagnosis | −0.89 (−2.23 - 0.42) | −0.71 (−1.29 - 0.16) | 0.628 |
HbA1c at diagnosis | 6.30 % (6.2% - 6.7%) | 5.75% (5.5% - 6.1%) | <0.001 |
OGTT at time zero: fasting glycaemia | 96 mg/dl (85 - 106) | / | / |
OGTT at time zero: glycaemia at 120’ | 214 mg/dl (192 - 233) | / | / |
F508 Homozygote | 17/23 | 15/23 | 0.522 |
F508 Heterozygote/class I-III | 5/23 | 8/23 | 0.326 |
No F508 deletion | 1/23 | 0/23 | 0.321 |