pH

k_on (M⁻¹∙s⁻¹)

k_off (s⁻¹)

Initial binding rate constants

11

2.3 ± 1.8 × 10⁴ (N = 8)

15.6 ± 2.6 (N = 8)

4.8 ± 1.9 × 10⁴ (N = 8)

6.45

−2.1 ± 0.7 × 10⁵ (N = 8)

20.9 ± 4.0 (N = 8)

6.2 ± 3.3 × 10³ (N = 8)