Pat #

Age

Gender

Hand

rs_Mean

Localiz.

NM Std.

Localiz.

ED

Mm

Comments

29

6

F

LH

L-temporal

L-parietal

67.1

Dx: Cortical Dysplasia. Interictal EEG showed left posterior quadrant discharges. PET showed complete left hemisphere hypometabolism. Was not operated.

28

17

F

RH

L-temporal

L-parietal

68.0

Dx: Viral Encephalitis. Interictal EEG with left parietal (P3) spikes. PET showed left central and left temporal hypometabolism. Was not operated.

8

11

M

RH

L-temporal

R-temporal

76.0

Dx: Cortical Dysplasia. Interictal EEG showed independent bilateral temporal dischargers. Left ones were rare. Patient had right temporal lobectomy. Asymptomatic since then.

10

10

F

RH

L-frontal

R-mesial-

occipital

R-temporal

R-mesial-

occipital

96.1

Dx: Cortical Dysplasia. Two rs-Mean ROIs were found. The largest ROI was chosen for comparison. Interictal EEG showed right temporo-occipital discharges. EEG-source localization showed right-mesial occipital dipole in one solution and the right inferior posterior temporal in a second solution. Ictal EEG showed right centro-parietal discharges. rs-Mean showed evident low signal in the right parietal area.

11

15

F

LH

L-temporal

R-temporo-

parietal

93.3

Dx: Non lesional. Ictal EEG showed right temporal onset. rs-Mean has clear low values in the right temporo-parietal area. Seizure-to-rs-fMRI interval was more than 72 hours.

21

8

M

RH

L-temporal

L-temporal

82.0

Dx: Non lesional. Ictal EEG showed right frontal onset. The rs-Mean showed evident low signal area in the right frontal lobe. Seizure-to-rs-fMRI interval was 1 hour. The patient underwent right frontal resection. Has remained seizure free for more than 12 months.

20

4

F

RH

R-occipital

R-frontal

71.5

Dx: Tuberous Sclerosis. Ictal EEG showed right frontal onset in majority of registries, but one episode was documented with “convincing right occipital onset”. The rs-Mean had clear areas of very low intensities in both frontal lobes (right more than left). Seizure-to-rs-fMRI interval was more than 72 hours. Patient was not operated.

26

11

1M

RH

L-occipital

R-temporal

96.0

Dx: Tuberous Sclerosis. Ictal and interictal EEG showed bilateral independent focus in posterior quadrants. Both SPECT and rs-Mean showed more than one area of hyper intensity. Comparison was performed between more conspicuous areas. rs-Mean showed in addition to the left-occipital, left frontal, right parietal. SPECT findings were subtle. Clinically, the patient had seizures with right eye and head version to the right. The patient was not operated.