Parameters correlated with cytotoxicity of Tp1_214-224 pulsed PBMC at effector: target ratio of 20

Spearman’s correlation coefficient

P-Value

% Total Tp1 tetramer positive cells

0.9

0.004

% Tp1 tetramer positive cells times MFI

1

<0.001

% perforin positive cells (gated on Tp1 tetramer positive cells)

0.9

0.004

MFI for perforin (gated on Tp1 tetramer positive cells)

0.8

0.021

% perforin positive cells times MFI for perforin (gated on tetramer positive cells)

1

<0.001