Respectively compared to control

Up-regulated genes

414

273

273

662

395

383

383

238

DG in up-regulated genes

173

147

147

265

187

188

188

61

The percentage of DGs

41.79%

53.85%

53.85%

40.03%

47.34%

49.09%

49.09%

25.63%

Chi-square value

9.6156

14.9637

0.2368

33.6225

p-value

P = 0.001929

P = 0.000110

P = 0.626527

P = 0.000000

Down-regulated genes

382

252

252

728

272

222

222

235

DG in down-regulated genes

127

119

119

212

180

153

153

110

The percentage of DG

33.25%

47.22%

47.22%

29.12%

66.18%

68.92%

68.92%

46.81%

Chi-square value

12.489

27.4299

0.4179

22.8428

p-value

p = 0.000409

p = 0.000000

p = 0.517987

p = 0.000002

Comparison between the two groups (for further analysis)

Up-regulated genes

297

156

122

511

209

197

301

156

DG in up-regulated genes

126

85

71

199

82

109

150

42

The percentage of DG

42.42%

54.49%

58.20%

38.94%

39.23%

55.33%

49.83%

26.92%

Chi-square value

5.9834

14.9222

10.5422

22.1373

p-value

p = 0.014441

p = 0.000112

p = 0.001167

p = 0.000003

Down-regulated genes

311

181

143

619

175

125

166

179

DG in down-regulated genes

116

111

79

189

106

95

119

95

The percentage of DG

37.30%

61.33%

55.24%

30.53%

60.57%

76%

71.69%

53.07%

Chi-square value

24.0081

31.1211

7.845

12.6671

p-value

p = 0.000001

p = 0.000000

p = 0.005096

p = 0.000372