LDH (U/L) |
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|
|
|
|
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| |
Mean ± SD | 354 | ±107.94 | 285 | ±36.25 | 368.91 | ±112.68 | 0.051• | |
Median (Range) | 340 | (190 - 540) | 295 | (200 - 320) | 400 | (190 - 540) | ||
≤350 U/L | 23 | (51.1%) | 8 | (34.8%) | 15 | (65.2%) | 0.004 | |
>350 U/L | 22 | (48.9%) | 0 | (0%) | 22 | (100%) | ||
B2-microglobulin (mg/L) |
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|
|
|
|
|
| |
Mean ± SD | 2.91 | ±0.99 | 2.03 | ±0.44 | 3.10 | ±0.98 | 0.006• | |
Median (Range) | 3 | (1.40 - 5) | 2 | (1.40 - 3) | 3 | (1.70 - 5) | ||
<3.5 mg/L | 29 | (64.4%) | 8 | (27.6%) | 21 | (72.4%) | 0.037 | |
≥3.5 mg/L | 16 | (35.6%) | 0 | (0%) | 16 | (100%) | ||
Coomb’s test |
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|
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|
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| |
Negative | 38 | (84.4%) | 8 | (21.1%) | 30 | (78.9%) | 0.321 | |
Positive | 7 | (15.6%) | 0 | (0%) | 7 | (100%) | ||
Lymphocytic doubling time |
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|
|
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|
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| |
<12 months | 21 | (46.7%) | 7 | (33.3%) | 14 | (66.7%) | 0.017 | |
>12 months | 24 | (53.3%) | 1 | (4.2%) | 23 | (95.8%) | ||
Cytogenetic analysis |
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| |
Normal | 20 | (44.4%) | 4 | (20%) | 16 | (80%) | 0.210 | |
del 13 | 4 | (8.9%) | 2 | (50%) | 2 | (50%) | ||
del 11 | 5 | (11.1%) | 0 | (0%) | 5 | (100%) | ||
Trisomy 12 | 6 | (13.3%) | 2 | (33.3%) | 4 | (66.7%) | ||
del 17 | 5 | (11.1%) | 0 | (0%) | 5 | (100%) | ||
Complex | 5 | (11.1%) | 0 | (0%) | 5 | (100%) | ||
CD38 (%) |
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| |
Mean ± SD | 23.79 | ±25.41 | 3.53 | ±2.38 | 28.17 | ±26.03 | 0.013• | |
Median (Range) | 8 | (0.30 - 91.59) | 4.41 | (0.30 - 5.95) | 27.61 | (0.60 - 91.59) | ||
<30% | 28 | (62.2%) | 8 | (28.6%) | 20 | (71.4%) | 0.017 | |
>30% | 17 | (37.8%) | 0 | (0%) | 17 | (100%) | ||
MCL-1 (%) |
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| |
Mean ± SD | 60.60 | ±41.98 | 36.64 | ±36.07 | 65.78 | ±41.79 | 0.102• | |
Median (Range) | 91.30 | (0.60 - 99.70) | 31.48 | (1.10 - 99.70) | 97.47 | (0.60 - 99.40) | ||
<25% | 18 | (40%) | 4 | (22.2%) | 14 | (77.8%) | 0.694 | |
>25% | 27 | (60%) | 4 | (14.8%) | 23 | (85.2%) | ||
ZAP-70 |
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|
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| |
<20% | 27 | (60%) | 2 | (7.4%) | 25 | (92.6%) | 0.045 | |
>20% | 18 | (40%) | 6 | (33.3%) | 12 | (66.7%) | ||
BCL-2/Bax ratio |
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|
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| |
Mean ± SD | 2.01 | ±1.50 | 0.80 | ±0.26 | 2.27 | ±1.53 | 0.006• | |
Median (Range) | 1.20 | (0.30 - 5) | 0.85 | (0.30 - 1.10) | 2 | (0.30 - 5) | ||
≤1.6 | 26 | (57.8%) | 8 | (30.8%) | 18 | (69.2%) | 0.014 | |
>1.6 | 19 | (42.2%) | 0 | (0%) | 19 | (100%) | ||