Sex | Parameters | Control group | YYH-C 24 mg/kg |
| YYH-C 48 mg/kg |
| YYH-C 96 mg/kg |
|
| TP (g/L) | 58.7 ± 2.3 | 57.5 ± 1.2 |
| 57.4 ± 1.5 |
| 59.8 ± 2.3 |
|
| ALB (g/L) | 34.8 ± 1.3 | 34.3 ± 0.7 |
| 34.8 ± 1.4 |
| 35.9 ± 1.6 |
|
| AST (U/L) | 145 ± 45 | 148 ± 13 |
| 145 ± 37 |
| 158 ± 104 |
|
| ALT (U/L) | 40 ± 9 | 43 ± 7 |
| 69 ± 18 |
| 85 ± 77 |
|
| ALP (U/L) | 62 ± 14 | 80 ± 8 | * | 93 ± 15 | *** | 76 ± 10 |
|
| γ-GT (U/L) | 1.09 ± 0.619 | 1.149 ± 0.26 |
| 1.39 ± 0.72 |
| 1.42 ± 0.71 |
|
| UREA (mmol/L) | 6.0 ± 0.4 | 6.2 ± 0.2 |
| 6.3 ± 0.6 |
| 5.9 ± 0.8 |
|
♂ | CRE (μmol/L) | 29.8 ± 2.9 | 28.6 ± 1.8 |
| 30.8 ± 2.6 |
| 27.8 ± 3.4 |
|
| GLU (mmol/L) | 8.5 ± 0.7 | 7.5 ± 0.5 |
| 9.8 ± 1.6 |
| 8.6 ± 0.4 |
|
| T-bil (μmol/L) | 3.6 ± 0.4 | 2.3 ± 0.3 | ** | 2.2 ± 1.0 | ** | 2.2 ± 0.8 | ** |
| T-cho (mmol/L) | 2.1 ± 0.4 | 1.9 ± 0.4 |
| 2.1 ± 0.6 |
| 2.0 ± 0.2 |
|
| TG (mmol/L) | 0.7 ± 0.3 | 0.3 ± 0.1 | ** | 0.5 ± 0.2 | * | 0.5 ± 0.2 | * |
| CK (U/L) | 598 ± 252 | 613 ± 155 |
| 278 ± 46 |
| 242 ± 59 |
|
| Na+ (mmol/L) | 144.7 ± 1.5 | 145.9 ± 2.1 |
| 147.4 ± 1.6 |
| 146.5 ± 1.9 |
|
| K+ (mmol/L) | 5.0 ± 0.3 | 4.9 ± 0.2 |
| 4.8 ± 0.2 |
| 4.6 ± 0.1 |
|
| Cl− (mmol/L) | 106.4 ± 1.4 | 107.6 ± 0.3 |
| 107.9 ± 1.2 |
| 107.9 ± 1.2 |
|
| TP (g/L) | 65.4 ± 3.1 | 69.9 ± 6.4 |
| 61.6 ± 2.7 |
| 66.9 ± 6.1 |
|
| ALB (g/L) | 38.4 ± 2.2 | 43.0 ± 4.0 |
| 38.2 ± 2.4 |
| 40.6 ± 4.1 |
|
| AST (U/L) | 89 ± 21 | 172 ± 121 |
| 93 ± 13 |
| 80 ± 15 |
|
| ALT (U/L) | 40 ± 11 | 71 ± 62 |
| 37 ± 12 |
| 39.± 12 |
|
| ALP (U/L) | 36 ± 9 | 32 ± 11 |
| 44 ± 15 |
| 39 ± 10 |
|
| γ-GT (U/L) | 0.80 ± 0.10 | 1.15 ± 0.44 |
| 1.21 ± 0.16 |
| 0.98 ± 0.30 |
|
| UREA (mmol/L) | 6.7 ± 0.7 | 5.8 ± 0.9 |
| 6.8 ± 1.0 |
| 7.1 ± 1.0 |
|
♀ | CRE (μmol/L) | 29.6 ± 2.9 | 23.4 ± 3.3 |
| 28.6 ± 1.9 |
| 31.0 ± 7.2 |
|
| GLU (mmol/L) | 7.3 ± 0.7 | 7.7 ± 0.4 |
| 7.7 ± 0.5 |
| 7.8 ± 0.7 |
|
| T-bil (μmol/L) | 3.1 ± 1.3 | 6.4 ± 4.1 |
| 2.9 ± 1.2 |
| 5.2 ± 6.4 |
|
| T-cho (mmol/L) | 2.3 ± 0.7 | 2.7 ± 0.6 |
| 1.9 ± 0.2 |
| 1.9 ± 1.2 |
|
| TG (mmol/L) | 0.4 ± 0.2 | 1.0 ± 0.5 |
| 0.5 ± 0.2 |
| 0.8 ± 0.9 |
|
| CK (U/L) | 251 ± 180 | 275 ± 169 |
| 206 ± 69 |
| 153 ± 100 |
|
| Na+ (mmol/L) | 145.0 ± 1.1 | 145.6 ± 0.6 |
| 143.8 ± 4.3 |
| 146.1 ± 1.3 |
|
| K+ (mmol/L) | 4.2 ± 0.2 | 4.2 ± 0.2 |
| 4.1 ± 0.2 |
| 4.2 ± 0.3 |
|
| Cl− (mmol/L) | 107.6 ± 1.3 | 108.5 ± 2.0 |
| 108.3 ± 0.6 |
| 107.8 ± 1.4 |
|