Sex | Parameters | Control group | YYH-C 24 mg/kg |
| YYH-C 48 mg/kg |
| YYH-C 96 mg/kg |
|
| TP (g/L) | 60.6 ± 3.2 | 59.1 ± 2.7 |
| 58.5 ± 2.9 |
| 59.8 ± 3.4 |
|
| ALB (g/L) | 35.3 ± 1.9 | 34.6 ± 1.4 |
| 34.6 ± 1.9 |
| 34.9 ± 1.9 |
|
| AST (U/L) | 172 ± 119 | 145 ± 35 |
| 121 ± 22 |
| 140 ± 116 |
|
| ALT (U/L) | 59 ± 44 | 52 ± 15 |
| 47 ± 9 |
| 73 ± 81 |
|
| ALP (U/L) | 89 ± 19 | 94 ± 14 |
| 92 ± 18 |
| 86 ± 15 |
|
| γ-GT (U/L) | 0.70 ± 0.70 | 0.81 ± 0.25 |
| 0.865 ± 0.27 |
| 0.76 ± 0.41 |
|
| UREA (mmol/L) | 6.7 ± 1.0 | 6.6 ± 1.1 |
| 6.1 ± 0.6 |
| 6.3 ± 1.0 |
|
♂ | CRE (μmol/L) | 31.8 ± 4.6 | 29.4 ± 4.2 |
| 29.3 ± 1.4 |
| 28.6 ± 3.8 |
|
| GLU (mmol/L) | 8.3 ± 1.0 | 7.9 ± 0.9 |
| 7.0 ± 0.4 | * | 7.4 ± 0.7 |
|
| T-bil (μmol/L) | 4.8 ± 1.3 | 4.3 ± 1.7 |
| 4.4 ± 1.1 |
| 4.1 ± 1.3 |
|
| T-cho (mmol/L) | 1.9 ± 0.4 | 1.9 ± 0.4 |
| 1.8 ± 0.4 |
| 2.0 ± 0.2 |
|
| TG (mmol/L) | 0.5 ± 0.1 | 0.4 ± 0.3 |
| 0.5 ± 0.2 |
| 0.5 ± 0.2 |
|
| CK (U/L) | 527 ± 179 | 489 ± 144 |
| 371 ± 187 | * | 167 ± 143 | *** |
| Na+ (mmol/L) | 146.0 ± 2.2 | 146.6 ± 1.3 |
| 146.5 ± 1.2 |
| 147.0 ± 1.0 |
|
| K+ (mmol/L) | 4.9 ± 0.3 | 5.0 ± 0.3 |
| 4.8 ± 0.3 |
| 4.5 ± 0.4 | * |
| Cl− (mmol/L) | 108.4 ± 1.4 | 108.2 ± 1.3 |
| 107.8 ± 1.2 |
| 107.9 ± 1.4 |
|
| TP (g/L) | 67.7 ± 3.2 | 68.2 ± 4.8 |
| 65.2 ± 3.6 |
| 65.7 ± 3.0 |
|
| ALB (g/L) | 41.4 ± 2.4 | 41.0 ± 2.3 |
| 39.2 ± 2.2 | * | 39.1 ± 1.8 | * |
| AST (U/L) | 113 ± 25 | 98 ± 13 |
| 106 ± 27 |
| 90 ± 20 |
|
| ALT (U/L) | 40 ± 8 | 35 ± 8 |
| 34 ± 9 |
| 38 ± 6 |
|
| ALP (U/L) | 35 ± 17 | 35 ± 9 |
| 34 ± 6 |
| 48 ± 21 |
|
| γ-GT (U/L) | 0.55 ± 0.28 | 0.80 ± 0.19 | * | 0.86 ± 0.16 | ** | 0.90 ± 0.21 | ** |
| UREA (mmol/L) | 6.1 ± 0.7 | 6.1 ± 0.7 |
| 6.3 ± 1.4 |
| 6.6 ± 0.9 |
|
♀ | CRE (μmol/L) | 29.4 ± 4.5 | 29.7 ± 1.9 |
| 30.4 ± 4.8 |
| 29.4 ± 2.8 |
|
| GLU (mmol/L) | 6.7 ± 0.6 | 7.3 ± 0.9 |
| 6.9 ± 0.6 |
| 7.3 ± 0.4 |
|
| T-bil (μmol/L) | 5.0 ± 1.7 | 5.9 ± 1.6 |
| 3.6 ± 1.3 | * | 4.2 ± 1.4 |
|
| T-cho (mmol/L) | 2.2 ± 0.5 | 1.8 ± 0.6 |
| 2.1 ± 0.6 |
| 2.2 ± 0.6 |
|
| TG (mmol/L) | 0.6 ± 0.26 | 0.66 ± 0.3 |
| 0.4 ± 0.2 |
| 0.4 ± 0.2 |
|
| CK (U/L) | 411 ± 164 | 319 ± 84 |
| 357 ± 195 |
| 238 ± 154 |
|
| Na+ (mmol/L) | 145.0 ± 1.7 | 146.1 ± 1.0 |
| 146.5 ± 1.8 |
| 146.6 ± 2.5 |
|
| K+ (mmol/L) | 4.2 ± 0.2 | 4.3 ± 0.2 |
| 4.4 ± 0.3 | * | 4.1 ± 0.3 |
|
| Cl− (mmol/L) | 106.7 ± 1.9 | 106.8 ± 1.3 |
| 106.1 ± 0.8 |
| 107.2 ± 1.3 |
|