Sex | Parameters | Control group | YYH-C 24 mg/kg |
| YYH-C 48 mg/kg |
| YYH-C 96 mg/kg |
|
| TP (g/L) | 57.7 ± 2.2 | 57.2 ± 1.7 |
| 54.6 ± 2.9 |
| 56.6 ± 2.1 |
|
| ALB (g/L) | 34.1 ± 1.2 | 33.9 ± 1.4 |
| 32.4 ± 1.8 |
| 33.8 ± 1.1 |
|
| AST (U/L) | 122 ± 24 | 123 ± 25 |
| 85 ± 17 | * | 76 ± 12 | ** |
| ALT (U/L) | 34 ± 3 | 40 ± 4 |
| 33 ± 3 |
| 35 ± 11 |
|
| ALP (U/L) | 104 ± 12 | 108 ± 24 |
| 109 ± 18 |
| 114 ± 24 |
|
| γ-GT (U/L) | 0.75 ± 0.23 | 0.71 ± 0.17 |
| 0.72 ± 0.21 |
| 0.72 ± 0.20 |
|
| UREA (mmol/L) | 7.8 ± 1.4 | 5.7 ± 0.8 | ** | 5.9 ± 0.9 | ** | 6.2 ± 0.7 | * |
♂ | CRE (μmol/L) | 33.4 ± 5.9 | 25.6 ± 2.9 |
| 28.2 ± 0.8 |
| 25.6 ± 4.2 |
|
| GLU (mmol/L) | 7.8 ± 0.6 | 7.4 ± 0.8 |
| 7.3 ± 0.4 |
| 6.9 ± 0.4 |
|
| T-bil (μmol/L) | 3.8 ± 0.8 | 3.6 ± 1.2 |
| 2.4 ± 0.8 |
| 3.2 ± 0.9 |
|
| T-cho (mmol/L) | 1.5 ± 0.20 | 1.6 ± 0.2 |
| 1.6 ± 0.2 |
| 1.6 ± 0.4 |
|
| TG (mmol/L) | 0.3 ± 0.0 | 0.4 ± 0.2 |
| 0.4 ± 0.2 |
| 0.4 ± 0.2 |
|
| CK (U/L) | 523 ± 163 | 496 ± 205 |
| 210 ± 95 |
| 114 ± 66 | * |
| Na+ (mmol/L) | 146.2 ± 2.3 | 147.7 ± 1.0 |
| 148.2 ± 0.9 |
| 149.5 ± 0.5 |
|
| K+ (mmol/L) | 4.6 ± 0.3 | 4.523 ± 0.3 |
| 4.4 ± 0.3 |
| 4.1 ± 0.4 |
|
| Cl− (mmol/L) | 106.9 ± 0.9 | 108.8 ± 1.2 | * | 108.9 ± 1.2 | * | 109.7 ± 1.4 | ** |
| TP (g/L) | 65.1 ± 2.3 | 63.8 ± 3.0 |
| 65.5 ± 6.4 |
| 66.8 ± 2.4 |
|
| ALB (g/L) | 40.4 ± 1.7 | 39.6 ± 2.4 |
| 40.5 ± 4.1 |
| 41.7 ± 1.6 |
|
| AST (U/L) | 108 ± 9 | 92 ± 16 |
| 102 ± 13 |
| 117 ± 17 |
|
| ALT (U/L) | 30 ± 5 | 30 ± 3 |
| 38 ± 7 |
| 38 ± 9 |
|
| ALP (U/L) | 55 ± 16 | 80 ± 27 |
| 44 ± 6 |
| 51 ± 8 |
|
| γ-GT (U/L) | 0.72 ± 0.18 | 0.8548 ± 0.18 |
| 0.76 ± 0.23 |
| 1.04 ± 0.33 |
|
| UREA (mmol/L) | 6.3 ± 0.6 | 7.5 ± 0.7 | * | 7.2 ± 0.9 |
| 8.0 ± 0.6 | ** |
♀ | CRE (μmol/L) | 29.8 ± 3.0 | 30.0 ± 2.0 |
| 24.6 ± 3.5 | ** | 30.4 ± 2.3 |
|
| GLU (mmol/L) | 6.7 ± 0.7 | 7.2 ± 0.6 |
| 6.9 ± 0.6 |
| 6.9 ± 0.3 |
|
| T-bil (μmol/L) | 2.8 ± 0.8 | 1.8 ± 0.4 |
| 2.7 ± 1.3 |
| 3.5 ± 0.7 |
|
| T-cho (mmol/L) | 2.2 ± 0.4 | 2.1 ± 0.6 |
| 2.3 ± 0.4 |
| 2.1 ± 0.4 |
|
| TG (mmol/L) | 0.3 ± 0.1 | 0.2 ± 0.0 |
| 0.4 ± 0.2 |
| 0.3 ± 0.1 |
|
| CK (U/L) | 399 ± 98 | 298 ± 86 |
| 399 ± 116 |
| 422 ± 196 |
|
| Na+ (mmol/L) | 148.4 ± 0.8 | 146.9 ± 1.2 |
| 147.7 ± 1.3 |
| 147.8 ± 0.5 |
|
| K+ (mmol/L) | 4.0 ± 0.1 | 4.1 ± 0.1 |
| 4.1 ± 0.2 |
| 4.1 ± 0.1 |
|
| Cl− (mmol/L) | 111.0 ± 1.5 | 108.3 ± 1.1 | ** | 108.7 ± 1.8 | * | 110.0 ± 1.0 |
|