Time periods

A1: 1990-1999

A2: 2000-2009

B: 2010-2014

Female study groups:

Fist study group, n = 160

Second study group, n = 88

Current study group, n = 65

Age, years

30 ± 10 years

37 ± 16 years

36 ± 14 years, % of 65

Diastolic hypertension RR ≥ 90 mmHg:

35 ± 14 years (33% of 160)

37%, 95 ± 7 mmHg, 41 ± 14 years

15%, 97 ± 11 mmHg, 42 ± 15 years

Fasting glucose (FG 90 - 119 mg/dl)

36 ± 14 years (23% of 160)

30%, 98 ± 8 mg/dl,

41 ± 18 years

14%, 98 ± 6 mg/dl, 48 ± 16 years

Figure 1: Self-reported smoking

30 ± 10 years (13% of 160)

47%, 17 ± 9 cig, 35 ± 13 years

35%, 13 ± 8, 28 ± 10 years

AHA: intake of ≥20 g ethanol/day

35 ± 10 years, 13%:45 ± 34 g

16%, 39 ± 17 g, 42 ± 11 years

6%, 16 ± 9 g, 48 ± 11 years

Hypertriglyceridemia ≥ 150 mg/dl

15 of 53 (28%), 30 ± 10 years

29% of 58, 257 ± 12, 41 ± 6 years

9%, 193 ± 48 mg/dl, 51 ± 11 years

Adiposity, BMI2 ≥ 29 kg/m²

35 ± 15 years (10% of 160)

36 ± 11 years (11% of 88)

45 ± 10 years (10% of 65)

High LDL-cholesterol ≥ 150 mg/dl

47 ± 18 years (13% of 160)

11%, 180 ± 30, 35 ± 14 years (11%)

17%, 169 ± 19, 49 ± 6 years

Low HDL-cholesterol < 50 mg/dl

35 ± 13 years, 15 of 53 (28%)

10% of years 41, 47 ± 9,

50 ± 21 years

12%, 45 ± 2 mg/dl, 43 ± 13

Albumin/triglycerides (Alb/Trig) < 40

not screened

11 of 22: 27 ± 5, 34 ± 8 years

22%, 29 ± 18, 48 ± 16 years

Figure 2: Urine pathology

31 ± 10 years (13% of 160)

40 ± 8 years (26% of 88)

39 ± 12 years, n = 6

Figure 2: Hematuria

16 of 160 (10%)

13 of 88 (15%)

N = 1

Albuminuria, proteinuria

5 of 160 (3%)

6 of 88 (7%)

n = 5 (30 ± 9 mg/l U-albumin)

AHA and gamma-GT ≥ 18U/l

35 ± 23 U/l

32 ± 21 U/l

17 ± 3 U/l