PARAMETERS | TECHNIQUES | |
| External Beam (Malaker et al.) | Brachytherapy (Duex et al.) |
No. of Keloids | 86 | 22 |
Radiotherapy Dose | 3750 cGy in once weekly | 1800 cGy in 6F × TID |
| 750 cGy/fraction × 5 weeks | 300 cGy/F 9 am, 3 pm, 9 pm |
Duration of treatment | 35 days | 2 days |
Follow up period | 25 yrs | 7 yrs |
Response | 97% complete regression | 85.4% complete response |
| 3% poor responder | 13.6% recurrence |
| 100% complete asymptomatic | 97% complete asymptomatic |
Long-term side effect | 15.5% telangiectasia | <1% telangiectatic |
Carcinogenesis | Nil reported | Nil reported |
Observations | Most effective independent of radiobiological restriction | Highly effective short treatment period compliant with accepted brachytherapy-radiobiology, but independent of fraction radiobiology require brachytherapy facility |
| Easily adopted in any basic radiotherapy center | Hence restricted due to logistics |