PARAMETERS

TECHNIQUES

External Beam (Malaker et al.)

Brachytherapy (Duex et al.)

No. of Keloids

86

22

Radiotherapy Dose

3750 cGy in once weekly

1800 cGy in 6F × TID

750 cGy/fraction × 5 weeks

300 cGy/F 9 am, 3 pm, 9 pm

Duration of treatment

35 days

2 days

Follow up period

25 yrs

7 yrs

Response

97% complete regression

85.4% complete response

3% poor responder

13.6% recurrence

100% complete asymptomatic

97% complete asymptomatic

Long-term side effect

15.5% telangiectasia

<1% telangiectatic

Carcinogenesis

Nil reported

Nil reported

Observations

Most effective independent of radiobiological restriction

Highly effective short treatment period compliant with accepted brachytherapy-radiobiology, but independent of fraction radiobiology require brachytherapy facility

Easily adopted in any basic radiotherapy center

Hence restricted due to logistics