| Treatment | Dose | Response Time (in seconds) | ||||
| 0 min | 30 min | 60 min | 90 min | 120 min | ||
| Control | 0.1 mL/mouse | 2.00 ± 0.00 | 2.60 ± 0.245 | 3.00 ± 0.447 | 3.60 ± 0.510 | 3.80 ± 0.374 |
| Standard | 5 mg/kg | 2.20 ± 0.200 | 2.40 ± 0.245** | 3.20 ± 0.374** | 4.20 ± 0.374*** | 5.20 ± 0.375*** |
| MEDM | 200 mg/kg | 2.40 ± 0.245 | 3.00 ± 0.316 | 3.40 ± 0.400 | 4.00 ± 1.049* | 4.40 ± 0.600*** |
| MEDM | 400 mg/kg | 3.00 ± 0.775 | 3.80 ± 0.374* | 4.00 ± 0.316*** | 5.00 ± 0.316*** | 5.20 ± 0.200*** |
| MEDM | 600 mg/kg | 2.20 ± 0.200 | 4.00 ± 0.316** | 4.40 ± 0.245*** | 4.80 ± 0.374*** | 5.60 ± 0.245*** |