Parameter

Estimate (95% CI*)

% IIV (95% CI*)

TBPREV

HAARTPREV

Baseline

Steady state

Baseline

Steady state

CL/FG/G (L/h/70kg)

11.8 (7.6 - 13.8)

19.8

16.7 (12.3 - 19.2)

29.0

54 (10.4 - 48.1)

CL/FG/T (L/h/70kg)

8.8 (5.9 - 10.8)

14.8

10.6 (6.5 - 13.3)

18.4

53 (6.9 - 43.8)

CL/FT/T (L/h/70kg)

3.9 (2.6 - 5.0)

6.5

1.8 (1.6 - 1.9)

3.1

23