Parameters

Unit

Intravenous (10 mg/kg)

Oral (200 mg/kg)

Mean

SD

Mean

SD

AUC_0−t

μg/mL*min

1044.23

201.13

146

9.88

AUC_0−∞

μg/mL*min

1131.45

159.52

325.33

69.73

MRT

h

0.74

0.29

15.41

4.17

T_max

min

29.72

13.87

/

/

C_max

ng/mL

561.47

100.33

/

/

t_1/2

h

0.85

0.19

10.47

3.25

AUMC_0−∞

H*h*ng/mL

9589.94

1369.04

98857.22

43873.27

V

L/kg

1.91

1.78

24.18

2.94

CL

L/h/kg

0.92

0.3

1.68

0.41

Bioavailability, F

0.69%