Validation parameter | % RSD of peak area in standard solution for four replicate injections (NMT 5.0%) | ||
2-hydroxy-5-methylpyridine | Pirfenidone | Iodobenzene | |
Specificity | 1.85 | 1.52 | 0.98 |
Determination of LOD & LOQ values | 0.71 | 1.77 | 1.71 |
Precision at LOQ | 1.44 | 0.98 | 2.14 |
Linearity study | 1.87 | 1.78 | 1.37 |
Accuracy | 2.08 | 1.22 | 0.65 |
System precision | 0.91 | 0.48 | 2.18 |
Method precision | 2.10 | 1.72 | 3.01 |
Intermediate precision | 0.45 | 1.78 | 2.05 |
Robustness study-actual | 1.50 | 1.24 | 1.36 |