| *Treatment Options | Day 0 | Control | Day 5 | Control | Day 10 | Control | Day 15 | Control | Day 20 | Control | Day 25 | Control |
| A1 | 8.52 ± 0.05 | 8.76 ± 0.75 | 4.45 ± 0.34 | 8.14 ± 0.66 | 1.06 ± 0.43 | 7.83 ± 0.52 | 0 | 5.14 ± 0.23 | 0 | 3.38 ± 0.34 | 0 | 3.38 ± 0.80 |
| B | 10.60 ± 0.76 | 8.76 ± 0.66 | 5.54 ± 0.66 | 8.14 ± 0.23 | 1.32 ± 0.96 | 7.83 ± 0.34 | 0 | 5.14 ± 0.78 | 0 | 3.38 ± 0.31 | 0 | 3.38 ± 0.89 |
| E | 10.24 ± 0.76 | 8.76 ± 0.22 | 5.35 ± 0.88 | 8.14 ± 0.29 | 1.27 ± 0.87 | 7.83 ± 0.63 | 0 | 5.14 ± 0.29 | 0 | 3.38 ± 0.34 | 0 | 3.38 ± 0.38 |
| K | 8.96 ± 0.96 | 8.76 ± 0.76 | 4.68 ± 0.68 | 8.14 ± 0.54 | 1.11 ± 0.74 | 7.83 ± 0.84 | 0 | 5.14 ± 0.15 | 0 | 3.38 ± 0.39 | 0 | 3.38 ± 0.60 |
| A1 + B | 9.84 ± 0.62 | 8.76 ± 0.19 | 5.14 ± 0.59 | 8.14 ± 0.14 | 1.22 ± 0.12 | 7.83 ± 0.18 | 0 | 5.14 ± 0.15 | 0 | 3.38 ± 0.25 | 0 | 3.38 ± 0.49 |
| A1 + E | 9.56 ± 0.80 | 8.76 ± 0.29 | 5.00 ± 0..12 | 8.14 ± 0.45 | 1.19 ± 0.39 | 7.83 ± 0.18 | 0 | 5.14 ± 0.39 | 0 | 3.38 ± 0.36 | 0 | 3.38 ± 0.60 |
| A1 + K | 8.92 ± 0.14 | 8.76 ± 0.16 | 4.66 ± 0.20 | 8.14 ± 0.35 | 1.11 ± 0.24 | 7.83 ± 0.36 | 0 | 5.14 ± 0.24 | 0 | 3.38 ± 0.43 | 0 | 3.38 ± 0.67 |
| B + E | 10.56 ± 0.83 | 8.76 ± 0.16 | 5.52 ± 0.3 | 8.14 ± 0.31 | 1.31 ± 0.16 | 7.83 ± 0.34 | 0 | 5.14 ± 0.34 | 0 | 3.38 ± 0.45 | 0 | 3.38 ± 034 |
| B + K | 9.44 ± 0.42 | 8.76 ± 0.45 | 4.48 ± 0.11 | 8.14 ± 0.24 | 1.06 ± 0.16 | 7.83 ± 0.45 | 0 | 5.14 ± 0.42 | 0 | 3.38 ± 0.24 | 0 | 3.38 ± 0.16 |
| E + K | 10.16 ± 0.53 | 8.76 ± 0.32 | 5.31 ± 0.39 | 8.14 ± 0.14 | 1.26 ± 0.91 | 7.83 ± 0.78 | 0 | 5.14 ± 0.38 | 0 | 3.38 ± 0.39 | 0 | 3.38 ± 0.19 |
| A1 + E + K | 9.76 ± 0.67 | 8.76 ± 0.67 | 4.82 ± 0.28 | 8.14 ± 0.48 | 1.15 ± 0.50 | 7.83 ± 0.89 | 0 | 5.14 ± 0.28 | 0 | 3.38 ± 0.45 | 0 | 3.38 ± 033 |
| B + E + K | 10.36 ± 0.33 | 8.76 ± 0.85 | 1.25 ± 0.35 | 8.14 ± 0.42 | 1.19 ± 0.19 | 7.83 ± 0.38 | 0 | 5.14 ± 0.44 | 0 | 3.38 ± 0.84 | 0 | 3.38 ± 043 |
| A1 + B + E | 10.00 ± 0.12 | 8.76 ± 0.78 | 5.23 ± 0.34 | 8.14 ± 0.33 | 1.24 ± 0.33 | 7.83 ± 0.23 | 0 | 5.14 ± 0.45 | 0 | 3.38 ± 0.56 | 0 | 3.38 ± 0.43 |
| A1 + B + K | 10.44 ± 0.27 | 8.76 ± 0.34 | 5.45 ± 0.21 | 8.14 ± 0.14 | 1.30 ± 0.25 | 7.83 ± 0.38 | 0 | 5.14 ± 0.21 | 0 | 3.38 ± 0.34 | 0 | 3.38 ± 014 |
| A1 + B + E + K | 10.20 ± 0.09 | 8.76 ± 0.19 | 5.00 ± 0.42 | 8.14 ± 0.09 | 1.04 ± 0.19 | 7.83 ± 0.29 | 0 | 5.14 ± 0.32 | 0 | 3.38 ± 0.19 | 0 | 3.38 ± 019 |
| A2 | 9.56 ± 0.21 | 8.76 ± 0.18 | 5.00 ± 0.23 | 8.14 ± 0.43 | 1.19 ± 0.44 | 7.83 ± 0.18 | 0 | 5.14 ± 0.34 | 0 | 3.38 ± 0.44 | 0 | 3.38 ± 0.43 |
| P | 9.72 ± 0.22 | 8.76 ± 0.42 | 5.08 ± 0.34 | 8.14 ± 0.13 | 1.21 ± 0.43 | 7.83 ± 0.32 | 0 | 5.14 ± 0.43 | 0 | 3.38 ± 025 | 0 | 3.38 ± 0.13 |
| A2 + P | 10.60 ± 34 | 8.76 ± 0.42 | 5.54 ± 0.39 | 8.14 ± 0.25 | 1.32 ± 0.11 | 7.83 ± 0.34 | 0 | 5.14 ± 0.11 | 0 | 3.38 ± 0.34 | 0 | 3.38 ± 0.56 |