Author | Type of study | Conclusion |
Demicheli R, et al. 1997 [37] | Experimental Mathematical Model | Two peaks after resection. Surgical trauma, essential to manifest the peaks of recurrences |
Peters CFJM, et al. 2006 [38] | Experimental & Clinicopathological | After partial liver resection, residual tumor shows aggressive and faster recurrence |
Schatten WE, 1958 [39] | Experimental | Rapid growth of large number of latent pulmonary metastasis after removal of primary in leg |
Lange PH, et al. 1980 [40] | Retrospective Pathological & Serological | Tumor progressed after cytoreductive surgery: clinical trial urged. Post resection recurrence of testicular tumors |
Demicheli R, et al. 2008 [41] | Review & Critical Appraisal | From tumor dormancy to surgery driven enhancement of growth and metastasis likely |
Baum M, et al. 2005 [42] | Review & Critical Appraisal | Surgery induced angiogenesis and proliferation of distant dormant micro-metastasis |
Lacy AM, et al. 2002 [43] | Randomized Prospective | Laparoscopy assisted colectomy is superior than open colectomy; Morbidity, hospital stay, recurrence and Ca-related death, less: due to less surgical tissue damage |
Mitsudomi T, et al. 1996 [44] | Retrospective | Post-surgical accelerated growth of undetectable residual cancer and dormant cancer cells |
Gunduz N, et al. 1979 [45] | Retrospective | Post-surgical increase in residual tumor size; conversion of G0 to proliferative phase; synchronization of sensitive phases |
Fisher B, et al. 1983 [46] | Experimental | Labelling Index (LI) peaks 3 days after tumor excision; Perioperative chemotherapy recommended |