Age at onset | 59.5 years (20 - 84) | n | % |
Sex | Male | 3 | 10% |
Female | 27 | 90% | |
Race | Caucasian | 18 | 60% |
African American | 11 | 37% | |
Unknown | 1 | 3% | |
Ulcer location | Toes | 3 | 10% |
Feet | 4 | 13% | |
Ankle | 7 | 23% | |
Leg | 11 | 37% | |
Thigh | 2 | 7% | |
≥3 sites | 5 | 17% | |
Ssc Type | Limited | 19 | 63% |
Diffuse | 4 | 13% | |
Overlap syndrome/NOS | 7 | 23% | |
Hypercoagulable state | abnormal antiphospholipid antibodies | 4 | 13% |
Clinical evidence | 1 | 3% | |
Comorbidities | Raynaud’s | 27 | 90% |
Digital ulcers | 16 | 53% | |
Osteolysis | 9 | 30% | |
Digit loss | 7 | 23% | |
Peripheral neuropathy | 18 | 60% | |
Diabetes | 2 | 7% | |
Hypertension | 20 | 67% | |
Vascular disease | Venous | 9 | 30% |
Arterial | 11 | 37% | |
Venous and Arterial | 2 | 7% | |
Tobacco use | Current | 4 | 13% |
Former | 6 | 20% | |
Never | 20 | 67% | |
Medications | PD5 inhibitor | 11 | 37% |
ERA | 7 | 23% | |
ACE/ARB | 8 | 27% | |
Anticoagulation | 3 | 10% | |
Antiplatelet | 18 | 60% | |
Calcium channel blocker | 25 | 83% | |
Pentoxyphylline | 8 | 27% | |
IV prostacyclin analog | 2 | 7% | |
Immunosuppressant use for Ssc at time of ulcer | Yes | 20 | 67% |
No | 10 | 33% |