S. No | Parameters | Cerulein induced chronic pancreatitis | Cerulein induced chronic pancreatitis (untreated) | Cerulein induced chronic pancreatitis treated with green tea extract (equivalent to 0.1, 0.2 and 0.5% EGCG) |
1 | Acini | Dyscohesive and reduction in acini | Dyscohesive cells at the periphery | Mildly dispersed acini |
2 | Ductules | Increased | Increased | Ductules seen in 0.1% and 0.2% EGCG group but not in 0.5% EGCG group Mice |
3 | Vacuoles | Minimal due to loss of acini | Vacuoles present | Observed only in 0.1% EGCG group |
4 | Inflammatory cells/high power field | ~170 | ~120 | 132 in 0.1% EGCG Group 63 in 0.2% EGCG Group 50 in 0.5% EGCG Group |
5 | Fibrosis | Slight increase in collagen around the acini and ducts | Fibrosis around ducts | No Fibrosis |