S. No

Parameters

Cerulein induced chronic pancreatitis

Cerulein induced chronic pancreatitis (untreated)

Cerulein induced chronic pancreatitis treated with green tea extract (equivalent to 0.1, 0.2 and 0.5% EGCG)

1

Acini

Dyscohesive and reduction in acini

Dyscohesive cells at the periphery

Mildly dispersed acini

2

Ductules

Increased

Increased

Ductules seen in 0.1% and 0.2% EGCG group but not in 0.5% EGCG group Mice

3

Vacuoles

Minimal due to loss of acini

Vacuoles present

Observed only in 0.1% EGCG group

4

Inflammatory cells/high power field

~170

~120

132 in 0.1% EGCG Group

63 in 0.2% EGCG Group

50 in 0.5% EGCG Group

5

Fibrosis

Slight increase in collagen around the acini and ducts

Fibrosis

around ducts

No Fibrosis