Demographic features

N (%)/mean ± SD

Age

Sex

Males

BSA

74 ± 44 months

75 (68%)

0.84 ± 0.32

Type of malignancy

ALL

AML

Hodgkin + Non Hodgkin

Miscellaneous (Ewing Sarcoma = 4, Wilms tumor = 5).

70 (64%)

12 (11%)

19 (17%)

9 (8%)

Type of anthracycline used

・ Doxorubicin

・ Daunorubicin

・ Both

59 (53.5%)

16 (14.5%)

35 (32%)

Cumulative anthracycline dose

<300 mg

>300 mg

95 (86%)

15 (14%)

Radiation therapy

24 (22%)

Down’s syndrome

8 (7%)

Culture proven sepsis

Gram positive bacteria

Gram negative bacteria

Gram positive and negative combine

fungus

47 (43%)

29 (61.7%)

8 (17%)

6 (12.8%)

4 (8.5%)

Cardiac dysfunction

・ Within a month dysfunction

Diastolic alone

Combine systolic and diastolic

・ Within a year dysfunction

Diastolic alone

Combine systolic and diastolic

15 (14%)

10/15 (67%)

5/15 (33%)

28 (25.4%)

12/28 (43%)

16/28 (57%)

Sign symptoms of cardiac failure

・ Within a month

・ Within a year

4 (3.6%)

18 (16%)

Pericardial effusion

・ Within a month

・ Within a year

9 (8.2%)

19 (17.1%)