Demographic features | N (%)/mean ± SD |
Age Sex Males BSA | 74 ± 44 months
75 (68%) 0.84 ± 0.32 |
Type of malignancy ALL AML Hodgkin + Non Hodgkin Miscellaneous (Ewing Sarcoma = 4, Wilms tumor = 5). |
70 (64%) 12 (11%) 19 (17%) 9 (8%) |
Type of anthracycline used ・ Doxorubicin ・ Daunorubicin ・ Both |
59 (53.5%) 16 (14.5%) 35 (32%) |
Cumulative anthracycline dose <300 mg >300 mg |
95 (86%) 15 (14%) |
Radiation therapy | 24 (22%) |
Down’s syndrome | 8 (7%) |
Culture proven sepsis Gram positive bacteria Gram negative bacteria Gram positive and negative combine fungus | 47 (43%) 29 (61.7%) 8 (17%) 6 (12.8%) 4 (8.5%) |
Cardiac dysfunction ・ Within a month dysfunction Diastolic alone Combine systolic and diastolic ・ Within a year dysfunction Diastolic alone Combine systolic and diastolic |
15 (14%) 10/15 (67%) 5/15 (33%) 28 (25.4%) 12/28 (43%) 16/28 (57%) |
Sign symptoms of cardiac failure ・ Within a month ・ Within a year |
4 (3.6%) 18 (16%) |
Pericardial effusion ・ Within a month ・ Within a year |
9 (8.2%) 19 (17.1%) |