Heartburn

6.36 ± 4.56

4.23 ± 3.85

1.92 ± 2.49

4.43 ± 4.11

<0.001

Regurgitation

7.46 ± 4.25

4.08 ± 3.58

2.60 ± 2.96

4.86 ± 4.21

<0.001

GERD

13.79 ± 6.32

8.23 ± 5.36

4.56 ± 3.93

9.23 ± 6.69

<0.001

Dyspepsia

6.24 ± 4.16

3.86 ± 3.30

2.47 ± 3.05

3.76 ± 4.35

<0.001

QOLRAD

Emotional distress

5.74 ± 1.17

6.36 ± 0.77

6.57 ± 0.72

0.83 ± 1.06

<0.001

Sleeping disturbance

5.75 ± 1.12

6.27 ± 0.78

6.57 ± 0.70

0.82 ± 1.05

<0.001

Food/drink problems

5.22 ± 1.17

6.07 ± 0.75

6.38 ± 0.72

1.16 ± 1.02

<0.001

Physical/social functioning

6.20 ± 0.80

6.56 ± 0.61

6.77 ± 0.47

0.57 ± 0.74

<0.001

Vitality

5.48 ± 1.14

5.94 ± 0.93

6.37 ± 0.79

0.89 ± 1.00

<0.001

GILQI

Sum Score

108.3 ± 16

115.8 ± 13.9

121.5 ± 14

13.15 ± 12.51

<0.001

SF-12

Sum Score

38.17 ± 5.02

39.12 ± 4.55

40.17 ± 4.57

2.00 ± 5.10

0.007