Factor

Patients’ characteristics

Sex

All female

Age

Median 58 years (range, 44 - 75 years)

Relapse

Yes: 14 patients

No: 9 patients

Interval between the final irradiation dose and RIOP diagnosis

Median 4 months (range, 1 - 10.5 months)

Pathology

IDC: 21 lesions

DCIS: 4 lesions

TNM

TisN0M0: 4 lesions

T1N0M0: 21 lesions

Radiation dose

50 Gy/25 fractions: 9 patients

60 Gy/30 fractions: 10 patients

42.56 Gy/16 fractions: 1 patient

53.2 Gy/20 fractions: 1 patient

Right 50 Gy/25 fractions and left 60 Gy/30 fractions: 2 patients

Boost

Yes: 12 patients

No: 9 patients

White blood cell count

Median 7000/ml (range, 4000 - 14,900/ml)

CRP

2.2 mg/dl (range, 0.05 - 15.48 mg/dl)

Normal (less than 0.30 mg/dl): 5

Borderline (0.36 mg/dl): 1

High (more than 0.70 mg/dl): 12

Hormone therapy

Yes: 18 patients

No: 5 patients

Chemotherapy

Yes: 4 patients

No: 19 patients

RIOP ratio in the whole lung

Median 7.4% (range, 0.7% - 17.7%)

Corticosteroids

Yes: 17 patients (use methylprednisolone: 6 patients)

No: 6 patients

Prednisolone per unit body weight

0.40 mg/kg (range, 0.21 - 1.2 mg/kg)

Prednisolone dose reduction rate

Median 0.25 mg/day (range, 0 - 0.85 mg/day)