PT

TENDER/AGE

SYMPTOMS

MRI BRAIN

MRI TIBIA

1

F/ 40

Headache

-Multiple lesions

-Bilateral,

-Periventricular and subcortical white matter

-Splenium and

-Left temporal lobe―Gd (-)

2

F/ 23

seizures

-<1 mm focal lesions

-Bilateral

-Periventricular and subcortical white matter

-Gd: enhancement in the subcortical white matter on the left Parietal and right frontal lobe

3

F/38

Swollen tibias

No neurological

-Subcortical lesions extended to the cortex in the left parietal lobe,

-Focal lesions in the deep white matter bilateral,

-Porencephalic lesions with peripheral gliosis on the left parietal lobe

-Gd: no pathologic enhancement

Myositis of the tibial muscles bilateral