Aloe vera
| Increases type III collagen synthesis. Induces the synthesis of hyaluronic acid. Induces granulation tissue formation in the remodeling phase Increases wound contraction. Increases macrophage activation markers. Stimulates fibroblasts and collagen synthesis. Regulates the expression of MMP-3 and TIMP-2 in the granulation tissue. | Ali F Sánchez M Sari Y Jamil M Tanaka M, Hashemi SA Tabandeh MR, Budai Babaee N Davis RH | 2021 2020 2018 2018 2015 2015 2014 2013 2012 1989 | [251] [252] [217] [253] [254] [255] [256] [257] [258] [250] |
Scrophularia striata
| Decreases the wound area and lymphocytes number, Enhanced the number of fibroblasts at the earlier stages Increased the number of fibrocytes at the later stages of wound healing. Alignment of the healing tissue, re-epithelilization and epithelial formation, Enhancement of the maturity of the collagen fibers and fibroblasts and large capillary-sized blood vessels | Chatzopoulos GS Kerdar T Haddadi R Ghashghaii A Tanideh N | 2022 2019 2019 2017 2015 | [260] [261] [262] [263] [259] |
Alternanthera sessilis
| Enhancement of cell migration | Muniandy K, Enechi OC Jalalpure SS | 2018 2013 2008 | [265] [266] [264] |
Euphorbiaceae species | Acceleration of the wound healing process and wound contraction. | Ahmed S, | 2016 | [267] |
Abelmoschus esculentus Okra | Increases angiogenesis during the wound healing process in oral cavity | Luthfi M, | 2020 | [269] |
Amla/ Emblic myrobalan Bilberry fruit/Vaccinium myrtillus Hawthorn berry/Crateagus oxycanthus Liquorice root/Glycyrrhiza glabral Neem extract Mango leaf The miswak/Miswaak, siwak, sewak Sesame oil Yellow dock root, Alfalfa leaf, Cinnamon bark, Turmeric root. | Benefic effects on gingivitis Antibacterial effect Collagen stabilization | Singh A, | 2011 | [268] |
Roots of Albizzia lebbeck | Antibacterial properties Enhancement of collagen synthesis Antioxidant activity. Acute oral toxicity | Joshi A, | 2013 | [270] |