Camellia sinensis
| Significant reduction in premature senescence after Local EGCG and systemic senolytic administration in bone defects Enhancement in osteogenesis by periodontal ligament cells Enhancement in anti-inflammatory and bone healing activity Enhancement in healing process, cell proliferation and attachment Inhibition of osteoblast migration Diminution of osteoclastic activity through its anti-oxidant property Improvement in healing process Increases osteogenic markers, proliferation and mineralization Increases cell proliferation Anti-oxidant properties thus increase periosteal cell viability for a short-term period Maximum bone regeneration in combination of tricalcium phosphate particles | Chu C, Xie Y, Soares IMV, Honda Y, Kawabata T, Katsumata Y, Kuroyanagi G, Hong JY, Kaida K, Mah YJ, Kamiya M, | 2019 2019 2019 2018 2018 2018 2017 2015 2015 2014 2012 | [147] [161] [146] [191] [192] [193] [194] [195] [196] [197] [198] |
Curcuma longa/ Curcumin
| Enhancement in osteoblastic cell viability and proliferation Mineralized bone formation increased Enhancement of osteoblastic cell viability Improvement in cell migration and differentiation Improvement in bone formation Enhancement in ALP expression and mineral deposition | Sarkar N, Bose S, Li Y, Jain S, | 2019 2018 2018 2016 | [149] [150] [151] [148] |
Coffea arabica Chlorogenic acid | Significant anti-bacterial property against K. pneumonia and S. aureus Enhancement of chondrogenesis, cartilage matrix synthesis and angiogenesis Enhancement in levels of bone turnover markers and cellular osteogenic differentiation | Palaniraj S, Cheng X, Fujita K, Zhou RP, | 2019 2018 2017 2016 | [153] [154] [155] [152] |
Coconut oil | periodontal tissue regeneration via expressions of tnf-α and tgf-β1 | Thahir | 2022 | [159] |