| Event | PBO/EDX N = 207 | EDX/EDX N =190 | Total N = 397 |
|
| n (%) | n (%) | n (%) |
| Patients with at least 1 event | 158 (76.3) | 129 (67.9) | 287 (72.3) |
| Headache | 27 (13.0) | 16 (8.4) | 43 (10.8) |
| Hyperhidrosis | 28 (13.5) | 12 (6.3) | 40 (10.1) |
| Nausea | 23 (11.1) | 13 (6.8) | 36 (9.1) |
| Erectile dysfunction | 9 (10.3) | 1 (1.4) | 10 (6.4) |
| Nasopharyngitis | 18 (8.7) | 7 (3.7) | 25 (6.3) |
| Tachycardia | 17 (8.2) | 8 (4.2) | 25 (6.3) |
| Insomnia | 14 (6.8) | 9 (4.7) | 23 (5.8) |
| Heart rate increased | 13 (6.3) | 9 (4.7) | 22 (5.5) |
| Upper respiratory tract infection | 10 (4.8) | 10 (5.3) | 20 (5.0) |
| Constipation | 12 (5.8) | 6 (3.2) | 18 (4.5) |