| Polymorphisms Genotypes/Alleles | Control N = 428 n (%) | Patients | |||||||
| Gastric Cancer |
| Gastric Ulcer |
| Atrophic Gastritis |
| Duodenal Ulcer |
| ||
| N = 100 n (%) | OR (95% CI), p | N = 105 n (%) | OR (95% CI), p | N = 102 n (%) | OR (95% CI), p | N = 72 n (%) | OR (95% CI), p | ||
| TLR2 rs7696323 C/C C/T + T/T C T | 251 (59.3) | 51 (51.0) | 1.40 (0.75 - 2.62), 0.295 | 68 (64.8) | 0.78 (0.47 - 1.32), 0.360 | 64 (62.7) | 0.68 (0.36 - 1.31), 0.260 | 38 (53.8) | 1.15 (0.68 - 1.94), 0.600 |
| 172 (40.7) | 49 (49.0) |
| 37 (35.2) |
| 38 (37.3) |
| 34 (46.2) |
| |
| 0.76 | 0.72 | 1.29 (0.79 - 2.12), 0.311 | 0.71 | 0.74 (0.48 - 1.15), 0.177 | 0.78 | 0.72 (0.42 - 1.24), 0.240 | 0.73 | 1.06 (0.70 - 1.62), 0.770 | |
| 0.24 | 0.28 |
| 0.29 |
| 0.22 |
| 0.27 |
| |
| TLR2 rs1898830 A/A A/G + G/G A G | 123 (29.0) | 29 (29.0) | 1.07 (0.53 - 2.13), 0.859 | 35 (33.3) | 0.96 (0.56 - 1.65), 0.887 | 32 (31.4) | 1.31 (0.64 - 2.67), 0.460 | 26 (36.1) | 0.88 (0.51 - 1.54), 0.660 |
| 301 (71.0) | 71 (71.0) |
| 70 (66.7) |
| 70 (68.6) |
| 46 (63.9) |
| |
| 0.54 | 0.56 | 1.02 (0.65 - 1.60), 0.931 | 0.49 | 1.18 (0.83 - 1.69), 0.354 | 0.53 | 1.29 (0.82 - 2.04), 0.276 | 0.61 | 0.89 (0.61 - 1.30), 0.557 | |
| 0.46 | 0.44 |
| 0.51 |
| 0.47 |
| 0.39 |
| |
| TLR2 rs3804099 T/T T/C + C/C T C | 213 (50%) | 55 (55.0) | 0.73 (0.39 - 1.37), 0.325 | 51 (48.6) | 1.00 (0.61 - 1.66), 0.990 | 54 (52.9) | 0.87 (0.46 - 1.65), 0.680 | 30 (41.6) | 1.27 (0.75 - 2.15), 0.380 |
| 213 (50%) | 45 (45.0) |
| 54 (51.4) |
| 48 (47.1) |
| 42 (58.4) |
| |
| 0.69 | 0.75 | 0.67 (0.41 - 1.10), 0.111 | 0.68 | 0.91 (0.62 - 1.34), 0.640 | 0.7 | 0.87 (0.54 - 1.41), 0.569 | 0.65 | 1.09 (0.73 - 1.60), 0.682 | |
| 0.31 | 0.25 |
| 0.32 |
| 0.3 |
| 0.35 |
| |
| TLR2 rs3804100 T/T T/C + C/C T C | 229 (53.8) | 60 (60.0) | 0.73 (0.39 - 1.39), 0.340 | 54 (51.4) | 1.10 (0.66 - 1.82), 0.713 | 56 (54.9) | 0.92 (0.49 - 1.75), 0.800 | 33 (45.8) | 1.30 (0.78 - 2.19), 0.340 |
| 197 (46.2) | 40 (40.0) |
| 51 (48.6) |
| 35 (45.1) |
| 39 (54.2) |
| |
| 0.72 | 0.78 | 0.64 (0.38 - 1.07), 0.088 | 0.71 | 0.96 (0.65 - 1.42), 0.827 | 0.72 | 0.90 (0.55 - 1.48), 0.686 | 0.68 | 1.10 (0.72 - 1.59), 0.740 | |
| 0.28 | 0.25 |
| 0.29 |
| 0.28 |
| 0.32 |
| |
| TLR2 rs7656411 G/G G/T + T/T G T | 141 (33.1) | 26 (26.0) | 1.48 (0.75 - 2.93), 0.258 | 34 (32.4) | 1.20 (0.70 - 2.05), 0.506 | 33 (32.4) | 1.79 (0.89 - 3.59), 0.100 | 29 (40.2) | 0.86 (0.50 - 1.48), 0.590 |
| 285 (66.9) | 74 (74.0) |
| 71 (67.6) |
| 69 (67.6) |
| 43 (59.8) |
| |
| 0.57 | 0.53 | 1.08 (0.69 - 1.70), 0.722 | 0.59 | 0.93 (0.65 - 1.33), 0.674 | 0.57 | 1.12 (0.71 - 1.77), 0.614 | 0.61 | 0.86 (0.59 - 1.26), 0.441 | |
| 0.43 | 0.47 |
| 0.41 |
| 0.43 |
| 0.39 |
| |
| TLR4 rs10759932 T/T T/C + C/C T C | 236 (56.1) | 68 (68.0) | 0.52 (0.26 - 1.02), 0.059 | 59 (56.2) | 0.97 (0.58 - 1.61), 0.905 | 61 (59.8) | 1.03 (0.54 - 1.97), 0.930 | 41 (56.9) | 0.97 (0.57 - 1.64), 0.900 |
| 185 (44.9) | 32 (32.0) |
| 46 (43.8) |
| 41 (40.2) |
| 31 (43.1) |
| |
| 0.75 | 0.81 | 0.76 (0.43 - 1.33), 0.333 | 0.74 | 1.09 (0.72 - 1.64), 0.691 | 0.77 | 1.17 (0.69 - 1.99), 0.554 | 0.76 | 1.03 (0.67 - 1.58), 0.906 | |
| 0.25 | 0.19 |
| 0.26 |
| 0.23 |
| 0.24 |
| |