Histological type of primary

Adenocarcinoma

661 (92.6%)

371 (91.2%)

290 (94.5%)

P = 0.09

Mucinous Adenocarcinoma/ Signet ring

53 (7.4%)

36 (8.8%)

17 (5.5%)

Distant metastasis

No

621 (87.0%)

347 (85.3%)

274 (89.3%)

P = 0.12

Yes

93 (13.0%)

60 (14.7%)

33 (10.7%)

Lymphatic vessel permeation

No

569 (79.7%)

313 (76.9%)

256 (83.4%)

P = 0.03

Yes

145 (20.3%)

94 (23.1%)

51 (16.6%)

Venous invasion

None

582 (81.5%)

326 (80.1%)

256 (83.4%)

P = 0.26

Yes

132 (18.5%)

81 (19.9%)

51 (16.6%)

Positive margin

No

667 (93.4%)

380 (93.4%)

287 (93.4%)

P = 0.95

Yes

47 (6.6%)

20 (6.5%)

27 (6.6%)

Preoperative radiotherapy

No

594 (83.2%)

311 (76.4%)

283 (92.2%)

P < 0.001

Yes

120 (16.8%)

96 (23.6%)

24 (7.8%)

Preoperative chemotherapy

No

633 (88.7%)

344 (84.5%)

289 (94.1%)

P < 0.001

Yes

81 (11.3%)

63 (15.5%)

18 (5.9%)

Postoperative radiotherapy

No

691 (96.8%)

395 (97.1%)

296 (96.4%)

P = 0.64

Yes

23 (3.2%)

12 (2.9%)

11 (3.6%)

Postoperative chemotherapy

No

487 (68.2%)

225 (55.3%)

262 (85.3%)

P < 0.001

Yes

227 (31.8%)

182 (44.7%)

45 (14.7%)

TNM stage

Stage I

187 (26.2%)

95 (23.3%)

92 (30.0%)

P = 0.01

Stage II

201 (28.2%)

105 (25.8%)

96 (31.3%)

Stage III

233 (32.6%)

147 (36.1%)

86 (28.0%)

Stage IV

93 (13.0%)

60 (14.7%)

33 (10.7%)