Variable

HR (95% CI)

P-value

Age (years)

0.975 (0.956 - 0.995)

0.014

Baseline AFP

1.011 (0.985 - 1.038)

0.414

Gender (male)

1.028 (0.591 - 1.787)

0.922

Cirrhosis

1.154 (0.676 - 1.972)

0.594

Child-Pugh score

2.033 (1.265 - 3.268)

0.003

MELD score

1.069 (0.982 - 1.163)

0.125

ECOG

0

1 (Ref.)

1

2.980 (1.877 - 4.708)

<0.001

2

17.01 (7.723 - 37.45)

<0.001

BCLC stage

A

1 (Ref.)

B

0.024 (0.003 - 0.208)

0.001

C

0.063 (0.008 - 0.525)

0.011

Vascular invasion

1.754 (1.127 - 2.729)

0.013

Metastasis

1.197 (0.770 - 1.861)

0.425

TPA

2.930 (1.891 - 4.541)

<0.001