Characteristics

Global

N = 114

TPA < 90

N = 53

TPA ≥ 90

N = 54

P-value

Follow-up (months), median (P₂₅ - P₇₅)

9.23 (4.58 - 19.55)

8.10 (4.17 - 12.72)

18.85 (8.27 - 32.22)

<0.001

Age (years), mean ± sd

64.2 ± 10.0

61.6 ± 10.5

66.8 ± 9.3

0.008

Baseline AFP, median (P₂₅ - P₇₅)

29.3 (7.7 - 217.5)

132.3 (29.8 - 1.000)

9.2 (4.9 - 20.7)

<0.001

Gender (male), n (%)

97 (85.1)

44 (83.0)

46 (85.2)

0.797

Cirrhosis, n (%)

96 (84.2)

43 (81.1)

47 (87.0)

0.568

Etiology, n (%)

0.485

Alcohol

47 (41.2)

20 (37.7)

23 (42.6)

Hepatitis C virus (HCV)

31 (27.2)

12 (22.6)

18 (33.3)

Alcohol + HCV

13 (11.4)

6 (11.3)

5 (9.2)

Hepatitis B virus (HBV)

1 (0.9)

0 (0.0)

1 (1.8)

Other

22 (19.2)

15 (28.4)

7 (13.1)

Child Pugh score, (5/6), n (%)

89 (78.1)

36 (67.9)

51 (94.4)

<0.001

MELD score, mean ± sd

8.92 ± 2.44

9.39 ± 2.71

8.41 ± 2.10

0.039

Platelets (u/100,000), median (P₂₅ - P₇₅)

126.0 (91.0 - 194.0)

134.0 (91.2 - 191.7)

126.0 (90.0 - 196.5)

0.595

ECOG, n (%)

0.004

0

73 (64.0)

29 (54.7)

43 (79.6)

1

30 (26.3)

17 (32.1)

11 (20.4)

2

11 (9.6)

7 (12.2)

0 (0.0)

BCLC stage, n (%)

0.036

A

1 (0.9)

B

24 (21.1)

7 (13.2)

17 (31.5)

C

89 (78.0)

56 (86.8)

37 (68.5)

Vascular invasion, n (%)

30 (26.3)

32 (60.4)

20 (37.0)

0.020

Metastasis, n (%)

30 (26.8)

12 (23.5)

14 (25.9)

0.824

Previous treatments, n (%)

0.018

Resection

17 (14.9)

6 (11.3)

10 (18.5)

PEI

8 (7.0)

1 (1.9)

7 (13.0)

RFA

2 (1.8)

2 (3.8)

0 (0.0)

TACE

41 (36.0)

14 (26.4)

23 (42.6)

Y90

1 (0.9)

1 (1.9)

0 (0.0)

None

45 (39.5)

29 (54.8)

14 (25.9)