Mean insulin glargine per day (unit/kg of actual weight)

<0.05

50

6.00

p = 0.0733 n.s.

≥0.05, <0.1

491

7.74

≥0.1, <0.2

788

4.70

≥0.2, <0.3

164

3.66

≥0.3, <0.4

39

7.69

≥0.4, <0.5

4

0.00

≥0.5

0

-

Unknown/not specified

93

3.23

-

Administration time of insulin glargine at baseline

Once daily

p = 0.6830 n.s.

Morning

739

6.09

Day time

34

2.94

Night

241

6.22

Before bedtime

612

4.74

Twice daily

Morning and night

1

0.00

Morning and before bedtime

0

-

Unknown/not specified

2

0.00

-

Administration time of insulin glargine at LOCFc)

Once daily

p = 0.3121 n.s.

Morning

741

6.07

Day time

29

0.00

Night

241

7.05

Before bedtime

599

4.51

Twice daily

Morning and night

9

0.00

Morning and before bedtime

8

12.5

Unknown/not specified

2

0.00

-

Concomitant OADsc)

DPP-4 inhibitorsc)

Absent

641

5.77

p = 0.7399 n.s.

Present

988

5.36

Sulfonylureas

Absent

465

3.01

p = 0.0039**

Present

1164

6.53

Biguanides

Absent

837

5.62

p = 0.9138 n.s.

Present

792

5.43

Thiazolidinediones

Absent

1360

4.93

p = 0.0271*

Present

269

8.55

α-glucosidase inhibitors

Absent

1139

5.09

p = 0.2395 n.s.

Present

490

6.53

Insulin secretagogues

Absent

1520

5.66

p = 0.5152 n.s.

Present

109

3.67

Number of concomitant OADs at baselinec)

1

477

3.77

p = 0.0709 n.s.

2

566

5.83

3

438

6.85

≥4

148

6.08