Incidence of hypoglycaemia

Total number of patients

% of patients with hypoglycaemia

Analysis^a)b)

Analysis population

1629

5.52

-

Sex

Male

1022

4.40

p = 0.0132^*

Female

607

7.41

Age (years)

<20

0

-

p = 0.0726 n.s.

≥20, <30

11

0.00

≥30, <40

65

4.62

≥40, <50

197

4.06

≥50, <60

352

4.26

≥60, <70

506

5.73

≥70, <80

363

6.61

≥80

102

6.86

Unknown/not specified

33

12.1

-

Age (years, elderly patients)

<65

903

4.54

p = 0.0938 n.s.

≥65

693

6.49

Unknown/not specified

33

12.1

-

Duration of diabetes (years)

<1

49

4.08

p = 0.0542 n.s.

≥1, <5

212

5.19

≥5, <10

305

3.93

≥10, <15

318

6.92

≥15

389

7.71

Unknown/not specified

356

3.65

-

Complications

Hepatic function disorder

Absent

1313

5.41

p = 0.6809 n.s.

Present

316

6.01

Renal function disorder

Absent

1251

4.88

p = 0.0404^*

Present

378

7.67

Diabetic nephropathy

Absent

1262

4.91

p = 0.0513 n.s.

Present

367

7.63

Diabetic retinopathy

Absent

1392

5.17

p = 0.1642 n.s.

Present

237

7.59

Diabetic neuropathy

Absent

1386

5.05

p = 0.0658 n.s.

Present

243

8.23

Hypertension

Absent

851

4.94

p = 0.2801 n.s.

Present

778

6.17

Dyslipidaemia

Absent

783

3.58

p = 0.0010^**

Present

846

7.33

Dose and the administration time of insulin glargine

Mean dose of insulin glargine (unit/day)

<5

302

9.60

p = 0.0004^***

≥5, <10

832

5.41

≥10, <15

358

3.35

≥15, <20

93

4.30

≥20, <30

38

0.00

≥30, <40

4

0.00

≥40

0

-

Unknown/not specified

2

0.00

-