Drug

Adverse effects

Vortioxetine

2.5 mg

Vortioxetine

5 mg

Vortioxetine 10 mg

Vortioxetine 15 mg

Vortioxetine 20 mg

Overall

Duloxetine 60 mg

60 mg

Diarrhea

0.58 [0.29 - 1.15]

0.69 [0.34 - 1.41]

0.77 [0.30 - 2.01]

1.84 [0.76 - 4.41]

1.53 [0.79 - 2.96]

0.97 [0.66 - 1.44]

1.44 [0.98 - 2.13]

Dry mouth

0.92 [0.31 - 2.73]

1.17 [0.70 - 1.95]

0.52 [0.19 - 1.43]

0.97 [0.51 - 1.85]

1.60 [0.89 - 2.87]

1.10 [0.83 - 1.46]

2.75 [1.51 - 5.01]

Dizziness

0.98 [0.44 - 2.19]

0.98 [0.51 - 1.87]

0.57 [0.20 - 1.61]

1.57 [0.33 - 7.44]

1.81 [0.29 -11.25]

1.14 [0.72 - 1.82]

2.54 [1.57 - 4.12]

Fatigue

0.50 [0.15 - 1.69]

1.23 [0.56 - 2.69]

0.98 [0.19 - 4.93]

1.76 [0.72 - 4.32]

0.44 [0.02 - 9.20]

0.84 [0.39 - 1.80]

3.12 [1.88 - 5.19]

Headache

0.98 [0.62 - 1.55]

0.80 [0.47 - 1.37]

0.74 [0.39 - 1.42]

1.42 [0.87 -2.32]

1.27 [0.72 - 2.23]

1.01 [0.80 - 1.27]

1.07 [0.77 - 1.48]

Nausea

1.83 [1.12 - 2.99]

2.87 [1.94 - 4.23]

2.90 [1.46 - 5.78]

3.73 [2.42 - 5.76]

4.00 [2.60 - 6.14]

3.04 [2.47 - 3.37]

4.93 [3.75 - 6.60]