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| 4 | (S)-2 from 4 | (S)-3 | (R)-2 | ||
Entry | Substrate | n | Yield (%) | Ee (%)b | Yield (%) | Ee (%)b | Yield (%) | Ee (%)c |
1 | 4a | 2 | 33 | 83 | 39 | 83 | 62 | >99 |
2 | 4b | 3 | 25 | >99 | 48 | 99 | 93 | >99 |
3 | 4c | 4 | 25 | 99 | 50 | >99 | 96 | >99 |
4 | 4d | 5 | 25 | 97 | 45 | 97 | 75 | >99 |
5 | 4e | 6 | 25 | 90 | 45 | 85 | 75 | 98 |
6 | 4f | 8 | 30 | 80 | 50 | >99 | 80 | >99 |