Week	Group	Symptom, −	Symptom, +	Chi-square test p-value
1 - 3	Placebo	893	157	0.014*
1 - 3	GK-1	839	106	0.014*
4 - 6	Placebo	904	146	0.282
4 - 6	GK-1	829	126	0.282
7 - 9	Placebo	864	186	<0.001**
7 - 9	GK-1	899	46	<0.001**
10 - 12	Placebo	862	179	<0.001**
10 - 12	GK-1	898	41	<0.001**