Week	Group	Symptom, −	Symptom, +	Chi-square test p-value
1 - 3	Placebo	875	175	0.543
1 - 3	GK-1	797	148	0.543
4 - 6	Placebo	836	214	0.065
4 - 6	GK-1	783	162	0.065
7 - 9	Placebo	834	216	<0.001**
7 - 9	GK-1	843	102	<0.001**
10 - 12	Placebo	843	198	<0.001**
10 - 12	GK-1	868	71	<0.001**