CAR Antigen | Institute | Sample | Participants Effective Number | Outcome | Year of Publishing | Ref. | |
Number (M/F) | Age | ||||||
CD138 2nd 4-1BB | Chinese PLA general Hospital | 5 (1/4) | Adult | 5 | 4SDj | 2015 | [57] |
BCMA 2nd 4-1BB | University of Pennsylvania | 11f |
| 6k | 1CR; 1PR; 1SD | 2016 | [140] |
BCMA 2nd 4-1BB (bb2121) | Bluebird Bio | 9f |
| 9 | 2CRs in a cohort of 15 * 107 CAR-T cells; 1PR in a cohort of 5.0 * 107 CAR-T cell, 1PR in the cohort of 15 * 107 CAR-T cells and 2PR in a cohort of 45 * 107 CAR-T cell; 1SD in the cohort of 5.0 * 107 CAR-T cell and another is the cohort of 45 * 107 CAR-T cell. | 2017 | [141] |