BLOOD GLUCOSE LEVELS (mg/dl)

Groups

0 hr

1^st hr

3^rd hr

5^th hr

7^th hr

3^rd day

5^th day

7^th day

Normal Control

76.80 ± 4.74

77.80 ± 4.67

75.80 ± 4.22

75.00 ± 3.42

71.00 ± 1.30

76.60 ± 10.2

111.00 ± 9.47

87.40 ± 7.33

Diabetic Control

379.20 ± 12.5

381.60 ± 14.1

389.00 ± 12.0

384.00 ± 13.5

401.5 ± 19.9

480.8 ± 24.8

481.0 ± 36.5

479.8 ± 23.9

Glibenclamide 0.5 mg/kg

502.40 ± 6.71

417.20 ± 6.14**

348.6 ± 10.0**

293.20 ± 7.50**

246.0 ± 14.3**

192.4 ± 30.4**

158.0 ± 23.4**

150.4 ± 23.3**

CO 50 mg/kg

376.2 ± 46.0

370.2 ± 48.8ns

359.0 ± 45.5ns

328.8 ± 33.4ns

324.5 ± 34.2*

310.2 ± 33.8*

273.4 ± 26.3**

253.2 ± 32.1**

CO 100 mg/kg

483.00 ± 8.40

471.0 ± 13.1ns

456.2 ± 11.1ns

429.0 ± 12.9**

406.4 ± 12.6**

358.0 ± 13.7**

291.2 ± 18.9**

229.5 ± 15.2**