The category of anticancer medication

Total

Hiccups (n = 48)

Non-hiccups (n = 244)

P-value

Odda ratio

95% CI

Platinum drugs

130

40

90

<0.0001

8.56

3.84 - 19.09

Alkylating agents

41

5

36

0.5038

0.67

0.25 - 1.81

Antimetabolite agents

107

32

75

<0.0001

4.51

2.33 - 8.71

Antitumor antibiotic agents

46

8

38

0.83

1.08

0.47 - 2.50

Microtubule Inhibitors

81

4

77

0.0007

0.20

0.07 - 0.57

Topoisomerase inhibitors

37

12

25

0.0086

2.92

1.35 - 6.33

Molecular-target agents (Monoclonal antibodies）

32

3

29

0.3197

0.49

0.14 - 1.69

Molecular-target agents (Small molecules）

16

2

14

1

0.71

0.16 - 3.25