Suggestions for pharmacological treatment of depressive episodes with mixed features | |
Drug selection | Drug recommendations |
Single drug | Valproate, lithium salt, quetiapine |
Suitable for | Valproate/Lithium + quetiapine/olanzapine |
Not recommended | Antidepressants (for bipolar depressed patients, transcranial magnetic stimulation combined with mood stabilizers has a lower risk of transient mania compared to antidepressants) |