Experimental model

Solved disease

Experimental material

The experimental results

Reference

3D

human-tissue

models

Atherosclerosis

Paclitaxel (PTX)

It suggested excellent biological characteristics and potential treatment effects of the nanoparticles optimized in vitro

[1]

3D model set up by crosslinking HA with alginate

Breast cancer

Hyaluronan (HA)

The invasion and migration abilities of 4T-1 and SKBR3 cells are significantly enhanced by the presence of HA35

[2]

nanostructured 3D grids fabricated using electro-spinning technique

Screening of new drugs

Electrospun scaffolds

The scaffolds are transparent and thus allow observation of viable cells in time; standard fluorescence or colorimetric methods such can be used for evaluation of cells

[6]

Inflamed mucosa model (colon)

Chronic IBD (colon)

Budesonide/

fluoreceinamine

Prolonged anti-inflammatory effect was observed for 4 days

[18]

3D skin model

Skin

Squalene

Superior defensive and anti-wrinkle actions of squalane loaded fullerene-C60 was reported

[19]