Variables

Observation level

ORb (95% CI)

p-value

ORa (95% CI)

p-value

Watching

Non-observant

Age range

<5 years

68

216

1

≥5 years

30

54

0.56 (0.33 - 0.95)

0.032

0.96 (0.46 - 1.97)

0.91

Residence

Niamey

87

205

1

Other regions

11

65

2.50 (1.26 - 4.98)

0.007

1.81 (0.66 - 4.98)

0.24

Sex

M

44

136

1

F

54

134

0.80 (0.50 - 1.27)

0.35

Monthly income

>100,000

59

165

1

≥100,000

39

105

0.9725 (0.6 - 1.54)

0.87

Health Insurance

Yes

13

69

1

No

85

201

0.44 (0.23 - 0.84)

0.012

0.36 (0.16 - 0.84)

0.01

Diet

Monogamy

53

136

1

Polygamy

77

231

1.54 (0.8 - 2.67)

0.12

1.45 (0.74 - 2.82)

0.27

Schooling

Yes

36

202

1

No

98

270

0.19 (0.11 - 0.32)

<0.001

0.17 (0.10 - 0.30)

0.0001

Knowledge of the disease

Yes

95

233

1

No

3

37

5.02 (1.51 - 16.70)

0.0037

7.68 (2.20 - 26.72)

0.0014

Distance from center

<10 km

33

153

1

≥10 km

65

117

0.38 (0.23 - 0.62)

<0.0001

0.58 (0.33 - 0.99

0.04

Number of children with sickle cell disease in the family

≤ 2

7

39

1

>2

91

231

0.45 (0.19 - 1.05)

0.06

0.98 (0.35 - 2.76)

0.98

Occupation

0.007

Without

1

Private sector

1.93 (0.96 - 3.87)

Public sector

0.82 (0.36 - 1.86)

Educational level

<0.001

No level

1

Primary

0.10 (0.03 - 0.30)

Primary

0.30 (0.17 - 0.55)

Superior

0.13 (0.06 - 0.29)

Number of hospitalizations/year

≤3

9

23

1

>3

89

247

1.08 (0.48 - 2.43)

0.84

Number of crises per year

≤5

21

86

1

>5

77

184

0.58 (0.33 - 1.00)

0.05

0.70 (0.32 - 1.53)

0.38

Number of drugs per day

≤ 2

55

142

1

>2

43

128

1.15 (0.72 - 1.83)

0.0014

1.91 (0.90 - 4.06)

0.09

Use of personal vehicle

Yes

18

117

1

No

80

153

0.74 (0.41 - 1.31)

0.30

Stopping treatment

Yes

18

117

1

Boop

80

153

0.29 (0.16 - 0.51)

0.0001

0.15 (0.05 - 0.43)

0.0004

Form of sickle cell disease

SS

91

7

1

CS

248

22

1.15 (0.47 - 2.79)

0.75

Number of analyzes requested per year

<5

12

80

1

≥5

86

190

0.33 (0.17 - 0.63)

0.0006

1.06 (0.42 - 2.70)

0.88

Duration of sickle cell status

<5 years

46

52

1

≥5 years

181

89

0.43 (0.27 - 0.69)

<0.001

0.51 (024 - 1.10)

0.088